Prof. David Botstein[wp], the director of the Lewis-Sigler Institute at Princeton is with us at the CRI, 29 and 30 of March.

Two talks on consecutive days are planned that reflect Botstein's excellence both in quantitative biology research and education:

Monday March 29th
9h30- 11h30: "The fruits of the genome for society"
(presentation + open discussion)
Botstein's lab : http://www.princeton.edu/genomics/botstein/

16h00 - 19h00: Informal meeting with AIV & FdV students

Tuesday March 30th
9h30- 11h30 : "Merging education and research-The Lewis-Sigler institute"
(presentation + open discussion).

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The Lewis-Sigler Institute was established to innovate in research and teaching at the interface of modern biology and the more quantitative sciences. It has a quite unique collaborative structure where undergraduate students are integrated within the institute's research endeavors and all faculty, PhD and post-docs take part in the teaching, through interactive courses and lab work.
David Botstein, member of the American Academy of sciences and awardee of numerous prestigious prizes, has made fundamental contributions to modern genetics, including the discovery of many yeast and bacterial genes and the establishment of key techniques that are commonly used today as the method for mapping genes that laid the groundwork for the Human Genome Project.
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Short Biography
David Botstein (born 1942 in Switzerland) is an American biologist who has been the director of the Lewis-Sigler Institute for Integrative Genomics at Princeton University since 2003.
He graduated from Harvard in 1963 and received a Ph.D. from the University of Michigan in 1967. He then taught at the Massachusetts Institute of Technology, where he became a Professor of Genetics. In 1990, he became Chairman of the Department of Genetics at Stanford University. He has also worked for Genentech, as the Vice President - Science. Dr. Botstein was elected to the U.S. National Academy of Sciences in 1981 and to the Institute of Medicine in 1993.
Botstein is the director of the Integrated Science Program at Princeton University. Many of his students have gone on to be very successful in the field of molecular biology.
In 1980, Botstein and his colleagues Ray White, Mark Scolnick, and Ron Davis proposed a method for mapping genes that was used in subsequent years to identify several human disease genes including Huntington's and BRCA1. Variations of this method were used in the mapping efforts that predated and enabled the sequencing phase of the Human Genome Project.
In 1998, Botstein and his postdoctoral fellow Michael Eisen, together with graduate student Paul Spellman and colleague Patrick Brown, developed a statistical method and graphical interface that is widely used to interpret genomic data including microarray data.
Botstein has won the Eli Lilly and Company Award in Microbiology (1978), the Genetics Society of America Medal (1988), the Allen Award of the American Society of Human Genetics (1989) and the Gruber Prize in Genetics (2003).
He is the brother of the conductor Leon Botstein. Both of Botstein's parents were physicians.


David Botstein with Eva Maria Schoetz, Miroslav Radman and François Taddei, CRI conference